Reversal by aqueous extracts of Cistanche tubulosa from behavioral deficits in Alzheimer’s disease-like rat model: relevance for amyloid deposition and central neurotransmitter function

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منابع مشابه

Reversal by aqueous extracts of Cistanche tubulosa from behavioral deficits in Alzheimer’s disease-like rat model: relevance for amyloid deposition and central neurotransmitter function

BACKGROUND Cistanche tubulosa (Schenk) R. Wight (CT) is commonly used to treat forgetfulness by traditional Chinese physicians. This study presents the ameliorating effects of CT extract which was quantified with three phenylpropanoid glycosides in Alzheimer's disease (AD)-like rat model. METHODS Amyloid β peptide 1-42 (Aβ 1-42) intracisternally infused to rats by osmotic pump (Alzet 2002) wa...

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Varenicline Ameliorates Learning and Memory Deficits in Amyloid β(25–35) Rat Model of Alzheimer’s Disease

Introduction: Alzheimer’s disease (AD) is a enfeeble neurodegenerative disorder characterized by increased β-amyloid (Aβ) deposition and neuronal dysfunction leading to impaired learning and recall. Among proposed risk factors, impaired cholinergic transmission is a main cause for incidence of disease. Methods: In the present study, effects of the intracerebroventricularly administration of an ...

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The effect of nobiletin on behavioral function in elevated plus maze and forced swimming tests in intrahippocampal amyloid beta-induced model of Alzheimer's disease in the rat

Background and Objective: Alzheimer's disease (AD) is the most common form of dementia that is considered a chronic and progressive syndrome, that leads to the irreversible loss of neurons, particularly in the cortex and hippocampus. In this study, we considered whether nobiletin has any effect on behavioral function in elevated plus maze and forced swimming tests in amyloid beta-induced model ...

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varenicline ameliorates learning and memory deficits in amyloid β(25–35) rat model of alzheimer’s disease

introduction: alzheimer’s disease (ad) is a enfeeble neurodegenerative disorder characterized by increased β-amyloid (aβ) deposition and neuronal dysfunction leading to impaired learning and recall. among proposed risk factors, impaired cholinergic transmission is a main cause for incidence of disease. methods: in the present study, effects of the intracerebroventricularly administration of an ...

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ژورنال

عنوان ژورنال: BMC Complementary and Alternative Medicine

سال: 2014

ISSN: 1472-6882

DOI: 10.1186/1472-6882-14-202